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Compound InformationSONAR Target prediction
Name:

Hydralazine hydrochloride

Unique Identifier:LOPAC 00942
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C8ClH9N4
Molecular Weight:187.565 g/mol
X log p:10.866  (online calculus)
Lipinksi Failures1
TPSA24.72
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:1
Canonical Smiles:Cl.NNc1nncc2ccccc21
Class:Neurotransmission
Action:Inhibitor
Selectivity:MAO-A/B

Found: 24 nonactive as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: BY4741
Replicates: 8
Raw OD Value: r im 0.8406±0.101754
Normalized OD Score: sc h 1.0179±0.0315724
Z-Score: 0.5453±1.23898
p-Value: 0.520484
Z-Factor: -4.90236
Fitness Defect: 0.653
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:8|D4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.70 Celcius
Date:2005-04-07 YYYY-MM-DD
Plate CH Control (+):0.046637500000000005±0.00115
Plate DMSO Control (-):0.7662749999999999±0.04402
Plate Z-Factor:0.9298
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DBLink | Rows returned: 5
3637 phthalazin-1-ylhydrazine
9351 phthalazin-1-ylhydrazine hydrochloride
3775014 (phthalazin-1-ylamino)azanium
5538708 phthalazin-1-ylhydrazine
5538709 phthalazin-1-ylhydrazine

internal high similarity DBLink | Rows returned: 1
SPE01500334 1.0000

active | Cluster 5062 | Additional Members: 4 | Rows returned: 0
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